1-(2-Bromobenzoyl)-6,7-(methylenedioxy)isoquinoline

1-(2-Bromobenzoyl)-6,7-(methylene­dioxy)isoquinoline

In the title mol-ecule, C(17)H(10)BrNO(3), the mean planes of tricycle and bromo-phenyl fragments form a dihedral angle of 75.5 (1)°. In the crystal, π-π inter-actions [centroid-centroid distances = 3.556 (2) and 3.898 (8) Å] between the isoquinoline systems link mol-ecules into stacks parallel to the a axis. The crystal packing also exibits weak inter-molecular C-H⋯O hydrogen bonds.

4-Bromobenzoyl 4-bromobenzoate monohydrate

In the title compound, C(14)H(8)Br(2)O(3)·H(2)O, the organic and water mol-ecules both have crystallographically imposed C(s) symmetry. The dihedral angle between the aromatic rings is 45.76 (11)°. In the crystal structure, inter-molecular C-H⋯O and O-H⋯O hydrogen bonds link the mol-ecules into chains parallel to the a axis. No π-π stacking inter-actions are observed in the crystal structure.

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Drugs 2007; 67 (2): 215-235

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ISSN 2320-5407 International Journal of Advanced Research (2014), Volume 2, Issue 1, 67-78

Assist.Prof. Ali Ibrahim Ali Email: [email protected] alazziibrahim @gmail.com Chronic atrophic gastritis (CAG) characterized by chronic inflammation of gastric mucosa with loss of gastric glandular cells and replacement by intestinal-type epithelium and fibrous tissue. CAG may be associated with Helicobacter pylori infection. This study was designed to determine the role of NFkB signal...